Annexin V autoantibodies in rheumatoid arthritis.
نویسندگان
چکیده
منابع مشابه
Annexin V autoantibodies in rheumatoid arthritis.
OBJECTIVE To investigate the occurrence of anti-annexin V autoantibodies in sera of patients with rheumatoid arthritis to assess involvement with the disease and any relation to glucocorticoid treatment. METHODS Anti-annexin V antibodies were measured by an enzyme linked immunosorbent assay (ELISA) which used the purified human recombinant protein as antigen. RESULTS Concentrations of anti-...
متن کاملAutoantibodies in rheumatoid arthritis
(e--mail: [email protected]) Although the incidence and prevalence of individual autoimmune diseases are not high (table), the population burden of the disease is large and underestimated. Serum autoantibodies, which appear long before onset of clinical disease, are a characteristic feature, as recently emphasised by Markus Nielen and colleagues. Studying patients with rheumatoid arth...
متن کاملAutoantibodies to Posttranslational Modifications in Rheumatoid Arthritis
Autoantibodies have been associated with human pathologies for a long time, particularly with autoimmune diseases (AIDs). Rheumatoid factor (RF) is known since the late 1930s to be associated with rheumatoid arthritis (RA). The discovery of anticitrullinated protein antibodies in the last century has changed this and other posttranslational modifications (PTM) relevant to RA have since been des...
متن کاملNew autoantibodies in early rheumatoid arthritis
INTRODUCTION Rheumatoid arthritis (RA) is a chronic inflammatory joint disease causing articular cartilage and bone destruction. Since irreversible joint destruction can be prevented by intervention at the early stages of disease, early diagnosis of RA is important. In this study, we identified new autoantibodies in the sera of patients with early (less than one year) RA. METHODS We screened ...
متن کاملTherapeutic implications of autoantibodies in rheumatoid arthritis
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterised by the presence of autoantibodies. Their value for diagnostic/prognostic purposes has been well established. In contrast, their role in established disease and their associations with disease activity is less clear. Moreover, as evidence is accumulating that these autoantibodies are causally involved in certain key aspects...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1996
ISSN: 0003-4967
DOI: 10.1136/ard.55.12.895